Browsing by Author "Pahnke, Jens"

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    • The Norwegian childhood cancer biobank 

      Hermansen, Johanne Uthus; Wojcik, Dorota; Robinson, Nina; Pahnke, Jens; Haugland, Hans Kristian; Jamtøy, Ann-Helen; Flægstad, Trond; Halvorsen, Hanne; Lund, Bendik; Baumbusch, Lars Oliver; Munthe-Kaas, Monica Cheng (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-20)
      Background - The rapidly expanding era of “omics” research is highly dependent on the availability of quality-proven biological material, especially for rare conditions such as pediatric malignancies. Professional biobanks provide such material, focusing on standardized collection and handling procedures, distinctive quality measurements, traceability of storage conditions, and accessibility. For ...

    • Novel human melanoma brain metastasis models in athymic nude fox1nu mice: Site-specific metastasis patterns reflecting their clinical origin 

      Svendsen, Henrik Aasrum; Meling, Torstein Ragnar; Nygaard, Vigdis; Waagene, Stein; Russnes, Hege Elisabeth Giercksky; Juell, Siri; Rogne, Siril Gudmundson; Pahnke, Jens; Helseth, Eirik; Fodstad, Øystein; Mælandsmo, Gunhild Mari (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-06)
      Background: Malignant melanomas frequently metastasize to the brain, but metastases in the cerebellum are underrepresented compared with metastases in the cerebrum.<p> <p>Methods: We established animal models by injecting intracardially in athymic nude fox1<sup>nu</sup> mice two human melanoma cell lines, originating from a cerebral metastasis (HM19) and a cerebellar metastasis (HM86).<p> <p>Results: ...